Molecular, Cellular and Functional Biology of Hematopoiesis (BMCFH)


Persons in charge

Stéphane Giraudier – Nicolas Dulphy

Presentation

The Molecular, Cellular and Functional Biology of Hematopoiesis course aims to introduce the student to the molecular and cellular parameters governing the different concepts of proliferation, differentiation and cell death, common to all living cells, using a model of choice, the blood cell. The molecular mechanisms involved in the cellular dynamics of the hematopoietic cell are presented (from ontogeny to specific function and from pathology to therapeutic tools). This course is the national “reference” course for scientific students, physicians or pharmacists wishing to do basic and applied research in hematology.

Objectives

This scientific training aims at introducing the student to the molecular and cellular parameters governing the different concepts of proliferation, differentiation and cell death, based on a model of choice, the production of blood cells. The molecular mechanisms common to all living cells are presented:

a-from the stem cell to the differentiated cell,
b-from ontogeny to specific function and
c-from pathology to therapeutic tools.

  • To know and understand the theoretical bases of Hematology and Immunology in their molecular, cellular and physiopathological aspects.
  • To understand the principles of therapeutic strategies commonly used in Hematology.
  • To master the biotechnological and methodological approaches for the development of innovative therapies in Hematology.

For whom ?

Bac +4
Holders of : M1 or doctor/pharmacist (research path) or engineer

Capacity

25 students
Initial or continuing education

And after ?

Success rate: 99%.
Targeted training: Doctorate in Science, further studies in Medicine or Pharmacy.

Prerequisite

Very good level of knowledge in Molecular and Cellular Biology, Molecular Pathology, Oncology / Hematology. For health students, validation of research courses on the previously defined themes.
Experience of internship(s) in a laboratory is strongly recommended.
A good level of written and read English is required. Confirmed level of French.

Targeted skills

Disciplinary

  • Design and carry out R&D projects in Immuno-hematology and Oncology.
  • Implement technical and experimental approaches in relation to the projects and in application of a rigorous scientific approach.
  • Collect and analyze scientific and technical data.
  • Learn to critically read a research article.
  • Disseminate scientific information and results in writing or orally.
  • Know how to synthesize and debate scientific work.
  • Present  work orally.

Personal

  • Work independently and in a team.
  • Mastery of scientific English in the field.
  • Ability to argue and debate.
  • Mastery of computer languages used in the field.

Preprofessional

  • Designing R&D projects in Immuno-hematology and Oncology.
  • Project management.
  • Work independently and in a team.
  • Collaborate with external partners.
  • Prepare and maintain complex written documents (experimental reports, procedures, reports, projects).
  • Present work orally.